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KMID : 1240020200240000003
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International Neurourology Journal
2020 Volume.24 No. 0 p.3 ~ p.10
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Stem Cell Therapy for Neurogenic Bladder After Spinal Cord Injury: Clinically Possible?
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Kim Su-Jin
Cho Young-Sam
Park Jong-Mok
Na Young-Gil
Kim Khae-Hawn
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Abstract
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Neurogenic bladder (NB) after spinal cord injury (SCI) is a common complication that inhibits normal daily activities and reduces the quality of life. Regrettably, the current therapeutic methods for NB are inadequate. Therefore, numerous studies have been conducted to develop new treatments for NB associated with SCI. Moreover, a myriad of preclinical and clinical trials on the effects and safety of stem cell therapy in patients with SCI have been performed, and several studies have demonstrated improvements in urodynamic parameters, as well as in sensory and motor function, after stem cell therapy. These results are promising; however, further high-quality clinical studies are necessary to compensate for a lack of randomized trials, the modest number of participants, variation in the types of stem cells used, and inconsistency in routes of administration.
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KEYWORD
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Urinary bladder, Neurogenic, Spinal cord injury, Stem cells, Clinical trials
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